The DTIHIVE network of online Hubs are fun yet purposeful DTI & SEI virtual spaces strategically positioned at the intersection of low-middle income community (LMIC) needs, academia, and industry, to enable participants in academic/industry-based and independent interest groups/teams affiliated with the DTI HIVE virtual ecosystem to access and leverage the HIVE’s broad portfolio of assets and capabilities at lower cost to incubate DTIs & SEIs, and thus address applicable LMIC technological challenges through service-/project-based experiential e-learning, innovation and social entrepreneurship initiatives. The anticipated outcome is development and/or adoption of bespoke DTIs driving solutions and services benefiting LMICs and the world at large.